CHIEP

This activity aims to expand and validate the necessary tools and technologies that will make possible the production of new knowledge and its transition into practical applications in the area of health and medicine.

High- throughput research

The main objective is to catalyse progress in developing new research tools for modern biology including fundamental genomics that will enhance significantly data generation and improve data and specimen (biobanks), standardisation, acquisition and analysis. The focus will be on new technologies for: sequencing; gene expression; genotyping and phenotyping; structural and functional genomics; bioinformatics and systems biology.

Detection, diagnosis and monitoring

The aim is to develop visualisation, imaging, detection and analytical tools and technologies for biomedical research, for prediction, diagnosis, monitoring and prognosis of diseases, and for support and guidance of therapeutic interventions. The focus will be on a multidisciplinary approach integrating areas such as: molecular and cellular biology, physiology, genetics, physics, chemistry, biomedical engineering, nanotechnologies, microsystems, devices and information technologies.

Predicting suitability, safety and efficacy of therapies

The objectives are to develop and validate the parameters, tools, methods and standards needed for bringing to the patient safe and effective new or improved biomedicines. The focus will be on pharmacogenomics, developing and validating biological markers, targeting and delivery approaches, in silico, in vitro and in vivo methods and models and alternative testing strategies.

Innovative therapeutic approaches and interventions

The objectives of the area ‘Innovative therapeutic approaches and interventions’ are to research, consolidate and ensure further developments in advanced therapies and technologies with broad potential application. The focus will be on gene and cell therapy, regenerative medicine, transplantation, immunotherapy and vaccines.